Some relevant portions, just delivered:

I know I have a responsibility, if I am, as I hope to be, the Republican nominee for President, to unite the party and prepare for the great contest in November. And I am acutely aware that I cannot succeed in that endeavor, nor can our party prevail over the challenge we will face from either Senator Clinton or Senator Obama, without the support of dedicated conservatives, whose convictions, creativity and energy have been indispensible to the success our party has had over the last quarter century. Many of you have disagreed strongly with some positions I have taken in recent years. I understand that. I might not agree with it, but I respect it for the principled position it is. And it is my sincere hope that even if you believe I have occasionally erred in my reasoning as a fellow conservative, you will still allow that I have, in many ways important to all of us, maintained the record of a conservative. Further, I hope you will grant that I have defended many positions we share just as ardently as I have made my case for positions that have provoked your opposition. If not, thank you for this opportunity to make my case today.

...

Surely, I have held other positions that have not met with widespread agreement from conservatives. I won't pretend otherwise nor would you permit me to forget it. On the issue of illegal immigration, a position which provoked the outspoken opposition of many conservatives, I stood my ground aware that my position would imperil my campaign. I respect your opposition for I know that the vast majority of critics to the bill based their opposition in a principled defense of the rule of law. And while I and other Republican supporters of the bill were genuine in our intention to restore control of our borders, we failed, for various and understandable reasons, to convince Americans that we were. I accept that, and have pledged that it would be among my highest priorities to secure our borders first, and only after we achieved widespread consensus that our borders are secure, would we address other aspects of the problem in a wa y that defends the rule of law and does not encourage another wave of illegal immigration.

If you didn't watch, McCain was generally well-received. There were loud boos and catcalls when McCain brought up his immigration history, but otherwise, I think we can call the speech a success. Which is not to say that McCain has sealed the deal with conservatives, or with talk-radio.